712 Platelets , Vasoconstriction , and Nitroglycerin During Arterial Wall Injury
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چکیده
Endothelial injury in vivo is associated with platelet deposition and a localized plateletdependent vasoconstrictive response. To assess the influence of nitroglycerin on platelets and vasoconstriction, quantitative `111n-labeled platelet deposition (no platelets x 106/cm2) of the injured segment and the degree of angiographic vasoconstriction (percent diameter narrowing proximal and distal to the dilated segment) produced during injury by balloon angioplasty of the
منابع مشابه
Platelets, vasoconstriction, and nitroglycerin during arterial wall injury. A new antithrombotic role for an old drug.
Endothelial injury in vivo is associated with platelet deposition and a localized platelet-dependent vasoconstrictive response. To assess the influence of nitroglycerin on platelets and vasoconstriction, quantitative 111In-labeled platelet deposition (no platelets x 10(6)/cm2) of the injured segment and the degree of angiographic vasoconstriction (percent diameter narrowing proximal and distal ...
متن کاملPlatelets , Vasoconstriction , and Nitroglycerin During Arterial Wall Injury
Endothelial injury in vivo is associated with platelet deposition and a localized plateletdependent vasoconstrictive response. To assess the influence of nitroglycerin on platelets and vasoconstriction, quantitative `111n-labeled platelet deposition (no platelets x 106/cm2) of the injured segment and the degree of angiographic vasoconstriction (percent diameter narrowing proximal and distal to ...
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To determine whether percutaneous transluminal coronary angioplasty (PTCA) increases coronary artery luminal dimensions by stretching and injuring ("paralyzing") the smooth muscle of the arterial wall, we prospectively analyzed spontaneous changes and then intracoronary nitroglycerin-induced changes in segmental coronary artery diameters during the first 30 minutes after uncomplicated single-ve...
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BACKGROUND Experimental studies in vitro suggest that neutrophils can modulate platelet function and vasomotor responses. In the present study, the interactions among neutrophils, platelets, and arterial responses to injury in vivo were assessed. METHODS AND RESULTS The acute thrombotic and vasomotor responses of porcine carotid arteries to balloon injury in vivo were evaluated in three group...
متن کاملAlpha-adrenoceptor blockade prevents exercise-induced vasoconstriction of stenotic coronary arteries.
OBJECTIVES The study aimed to evaluate the role of alpha-adrenergic mechanisms during dynamic exercise in both normal and stenotic coronary arteries. BACKGROUND Paradoxical vasoconstriction of stenotic coronary arteries has been reported during dynamic exercise and may be due to several factors such as alpha-adrenergic drive, a decreased release of nitric oxide, platelet aggregation with rele...
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تاریخ انتشار 2005